7/24/2023 0 Comments Towermadness 2 miniUpon release, Appsgoer proclaims "you will be rewarded with an addictive, occasionally challenging strategy-demanding game." Android Central mentions "Beyond just the gameplay, this developer is doing all of the right things." Well-known app review site, Pocket Gamer, explains that "The game also balances its cheeky humour well with stages that will seriously challenge your forward-planning abilities." TouchArcade praises it as "an excellent tower defense game and expands upon the original in every fact". TowerMadness 2 received generally positive reviews. Overall rating of Tower Madness 2: 3D Defense is 4,6. Estimated number of the downloads is more than 1,000,000. Latest version of Tower Madness 2: 3D Defense is 2.1.1, was released on (updated on ). In Classic Mode, all maps and towers are unlocked. Tower Madness 2: 3D Defense is free Strategy game, developed by Limbic. If a player can win without losing any sheep, four stars are rewarded. In Invasion Mode, all UFOs are sent as quickly as possible, and the rounds have a bonus of +25% wool. A player's score is determined by the number of waves survived. In Endless Mode, there are an endless number of waves to defeat. In Normal Mode, there is a set number of enemy waves to destroy and UFOs arrive in intervals. There are four game modes: Normal, Endless, Invasion, and Classic. This can be used to unlock additional towers and tower levels in Xen’s Laboratory, the in-game shop. Wool, the in-game currency, is rewarded for completing or failing each map. Without Invasion Mode enabled, the highest possible stars earned are three. Stars rate how well a player did on each map based on how many sheep were saved, with the highest being four stars for completing a map with no sheep lost and with Invasion Mode enabled. Once all waves of enemies are destroyed or all sheep have been abducted, the game ends and you earn a certain number of stars and wool. Each enemy destroyed provides the player with more in-game coins to build new towers and upgrade existing towers. The player destroys the aliens by building towers. The goal of each alien is to abduct one sheep. Each wave arrives in intervals, or all waves can be sent at once if Invasion Mode is enabled. UFOs drop invading aliens on landing pads and the waves of enemies make their way to the base to abduct the sheep. The objective in TowerMadness 2 is to defend a base filled with a flock of sheep from waves of aliens by destroying the aliens with diverse weapons in the form of towers. TowerMadness 2 has game controller support. IPad owners, check out "TowerMadness HD" for the Pocket Gamer Readers' Choice iPad Game of the Year Award winning version of this game.TowerMadness 2 is a 3D tower defense strategy game, sequel to TowerMadness, for iOS and Android, developed by Limbic Software and released on January 23, 2014. Replays let you learn new strategies or share your games with the world through Twitter, Facebook, or email. The game offers enjoyable and colorful game play with a challenging, but fun experience. Global leaderboards, Game Center achievements, and Friend Scores so you can compare scores with your friends and the millions of players worldwide. Towermadness Splits - eastfasr Doodle Defense is a Tower Defense game that can be enjoyed by both casual and hardcore gamers. Think fast to defeat the 17 different types of alien enemies intent on stealing your sheep.Įndless mode lets you see how many waves you can withstand. Over 100 maps in diverse environments (35 available as expansion map packs). Play from an aerial view or zoom down to first person and get close to the action. FINALIST, Pocket Gamer Awards, Best Strategy/Simulation Game.WINNER, Best App Ever Awards, Best Strategy Game."It would be madness to miss this comes highly recommended." "If you’re a fan of Tower Defense games, do yourself a huge favor and check out TowerMadness." There are plenty of tower defense strategy games out there, but TowerMadness brings the genre to a new level." Evil aliens are coming to turn your beloved sheep into intergalactic scarves! Protect the flock using only quick thinking and the arsenal of upgradeable weaponry at your disposal. TowerMadness 2 is a 3D tower defense strategy game, sequel to TowerMadness, for iOS and Android, developed by Limbic Software and released on January 23, 2014.1 TowerMadness 2 has game controller support.
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7/24/2023 0 Comments Identify base64 encodingThis data must be processed differently, depending on what it's supposed to represent. It can be part of an image, it can be a part of an audio file or it can be a command that deletes half of your hard drive. A sequence such as 0010110 can mean many things. Why use Base64 Encoding?Ĭomputers work with 0s and 1s, so why bother converting this into another format? This means that it takes ~33% more space to store a Base64 encoded string as opposed to the original string. Note: 6 input characters are encoded into 8 characters in the end. In the end, we're left with the string QUJDMTIz - the Base64 representation of ABC123. Finally, using the Base64 chart, convert each decimal number into a Base64 character:.Get the decimal values of these binary chunks: If it's impossible to break it up into chunks of six, we have to pad the sequence. Convert the decimal value of each character into an 8-bit binary:.Take ASCII values of input characters separately:.There are five steps we take during this process: Manual Encodingįor example, let's say we have a string - ABC123 that we'd like to encode in Base64. Let's go ahead and manually encode a simple string to get a good idea of how the process works. Though, this is impractical due to difficulties in the encoding/decoding process. You could go higher than this and have each character represent 8 bits. So 64 characters of Base64 can be written as:Įach character is represented in 6 bits. Note: There is also a 65th character ( =), which serves a special meaning and it's called a padding character.Īs usual, when it comes to computers, numbers are represented in powers of 2. In Base64, as the name suggests, there are 64 characters used to encode binary data. While it does "obscure" the data to a degree, it's not a secure format by any means since reversing the encoding is trivial. What Base64 isn't is an encryption algorithm. It's very useful for storing image/audio information as strings of information. It's represented as printable ASCII characters where each Base64 character contains 6 bits of binary information. What is Base64?īase64 is a binary-to-text encoding scheme. Decoding is the reverse process of encoding - turning the encoded data back to the original format.Įncoding is all around us and computers heavily rely on different encoding formats to deliver and transfer information.įrom the latest cat image in your feed to the voice message you listened to over a messaging app - all of these were encoded on the sender-side, delivered to you, and decoded on the recipient-side.Įncoding makes sure that data remains intact and efficient for transport. The process of converting data by applying some techniques/rules into a new format is called encoding. 7/24/2023 0 Comments Zentangle patternsI’m always looking for new ways to express my feelings or my mood (cheesy, I know!), and that’s how I found out about zentangles! As an adult, I find them a creative and relaxing hobby that I can pick up for just a few spare moments or an entire evening.įor kids, coloring sheets as well as the repetitive patterns of zen coloring pages improve motor skills, stimulate creativity, contribute to better handwriting, teach color awareness, improve focus and hand to eye coordination, help learn about spacial awareness, and most importantly, improve confidence and self-esteem! The sun is created from a simple zentangle mandala art pattern with a floral flair and pencil drawn dots. The street is lined with concentric circles and straight lines that mimi brick patterns. The roof of the house has half circle doodles stacked on top of each other with a simple plant petal in the center of the home’s window. The alternating fence slat designs repeat petal lines opposite feathered lines. The zentangle line patterns are created for a full picture effect demonstrating a house, fence, street and sun. The last of our new patterns is full of more vertical lines, horizontal lines and individual row of small square images making up square tiles. Mandala zentangle #4 – Circles are arranged stacked on top of each other with curly lined doodles inside surrounding a single small circle in the center of the design.Mandala zentangle #2 – Round concentric lines are the base for the layering of petal-like shaped doodles in ovals and partial ovals with a complete circle at the middle.Mandala zentangle #1 – Half circle shape doodles are drawn together mirroring scales of a fish that concentrically become smaller toward the middle of the oval looped flower-like center.The meditative simple design of multiple structured patterns repeat within the circular shape: These four easy zentangle patterns could also be classified as mandala art as well. See if you can follow the original string that started the pattern and color accordingly or color the easy pattern within each shape. The first of our new patterns is a large traditional zentangle repetitive art pattern has been cut into 3 shapes: In our set of three pages of Zentangle art patterns in different variations ready for you to grab your favorite art supplies – pencils, colored pencils, markers, paint or glitter glue. Which zentangle art pattern will you color first? Zentangle Art to Color 7/24/2023 0 Comments Telltale games storywritingDoes that feel like a milestone for you guys?Ĭonnors: Some of it has to do with the content. There was a difference between what came before and what you achieved there. GamesBeat: It seems like the level of emotion that players get from your games really spiked with Walking Dead. And then Walking Dead put it all together with consequences. Poker introduced dialogue you could interrupt, with natural speech and natural conversation. The critical years, if you look at it, are from Back to the Future to Poker to Jurassic Park to Walking Dead. Telltale’s greatest strength is that we built the organization to support the process that got us to solving the problem of interactive narrative in games. You can’t just come out with an idea that instantly works and everyone says, “Wow, that’s brilliant.” Everything is a process. It’s hard to build something out of the box that just captures genius. We build this system to allow us to evolve through it. There are examples of everything that became Batman throughout those eight years. Any time we took on a franchise that wasn’t a traditional adventure game franchise, we tried to streamline things and make it flow better for people who didn’t know how to play adventure games. We stayed pretty traditional in the early days, but we were always thinking about how to move forward. I was thinking about the transition period. GamesBeat: How did you guys happen upon your formula?Ĭonnors: It’s funny you would ask that. Connors is still working on Telltale games, even without the CEO title. I interviewed him there. Here’s an edited transcript of our interview. Season Three of The Walking Dead is coming soon.Ĭonnors, who was CEO of the company until early 2015, gave a talk at the Gamelab event in Barcelona. Telltale has taken its formula of creating episodic games and is now broadening out with titles such as Game of Thrones, Batman, Minecraft: Story Mode, Tales from the Borderlands, and The Wolf Among Us. That was when we transitioned,” Connors said. “The critical years, if you look at it, are from Back to the Future to Poker to Jurassic Park to Walking Dead. But with the spectacular success of The Walking Dead in 2012, that all changed. The San Rafael, Calif.-based company makes slow-paced games with a lot of story, player choice, and fast-reaction button mashing. Telltale Games has always focused on interactive storytelling in its games, and it came into its own with the episodic release The Walking Dead, which is now in its third season. Register here.ĭisclosure: The organizers of Gamelab paid my way to Barcelona. But it will help.Connect with top gaming leaders in Los Angeles at GamesBeat Summit 2023 this May 22-23. Those of us who buy videogames may not be able to change that alone. They deserve laws that will protect them and jobs that will treat them well. Those of us who care can start shouting something else: that those who make our games deserve better. Often, this is used to enable the worst tendencies of the videogame industry, as small but vocal portions of the gaming audience cry out with casual disregard for other people. They know how reliant they are on the people who play games, who build loyalties to characters and studios and platforms. The people who run things, the publishers and CEOs and market analysts that drive decisions? They're terrified of their audiences. Because they're people.Īnd here, right here, is one of the dark secrets of the videogame industry. And, frankly, it should bother us even if their games don't matter to us. So when they're abused, and fired, and forced to go without having their needs met, it should bother us. It's natural to be protective of that.īut none of that happens without the people who make games. They've touched us, entertained us, changed us. Our voices are too often used not to defend the people who make games but the games themselves, clamoring loudly for our desire to see the fates of characters like The Walking Dead's Clementine, but quietly-if at all-for the people who brought those characters to life. But right now, one of the most glaring is us-the commentators and fans who play and love these games, and who too often prioritize the products over the people who make them. There are a lot of barriers to making that happen, some more surmountable than others. A well-organized collective of developers could push studios to change. Labor laws could protect these workers, prevent them from the worst abuses of an industry that regularly closes studios after even successful projects are completed. 7/24/2023 0 Comments Vimeo sexyBy Corinne Sullivan Published: Save Article YouTube Sexiness is subjective, ofc. Her previous films, "Jeanne & Mike: Original Art" & "Uncle Frank's House: An American Dream" were screened around the globe and won multiple awards. 55 Sexy Music Videos That’ll Have You Sweating Up a Damn Storm So many vids, so little clothing. This is the third short documentary by filmmaker Kathy Drasky. Share Vimeo videos, discussion and calls for help here. A treasure trove of family snapshots & home movies complement present-day interviews. Vimeo is the webs most supportive community of video creators, and this is the unofficial subreddit for it. It’s no wonder this is one of most popular bikinis. Our gorgeous statuesque bikini model Alison or the white see through fishnet micro g-string bikini that she’s wearing. "The Sexy Six: A Story of Lifelong Friendship" is the remarkable story of Helen, Ida, Jeanne, Marcia, Matty & Phyllis - collectively dubbed "the Sexy Six".įrom humble beginnings in a Connecticut factory town to making their way as career girls, wives & mothers, this short documentary explores the relationship of the six friends from first impressions to lasting ones. Thursday, Janu0 Micro Bikinis, Videos Fishnet, G-String, See Through, Sheer, Vimeo 3 It’s a coin toss deciding which is more popular. SHOP TIL YOU DROP! Our Sexy Six merch site is here: Flashing Asian Mom Open the Vimeo page with the video you want to save. 7/24/2023 0 Comments Projectile weaponsNote: Small and Medium creatures wielding reach weapons threaten all squares 10 feet (2 squares) away, even diagonally. A typical Large character wielding a reach weapon of the appropriate size can attack a creature 15 or 20 feet away, but not adjacent creatures or creatures up to 10 feet away. Most reach weapons double the wielder’s natural reach, meaning that a typical Small or Medium wielder of such a weapon can attack a creature 10 feet away, but not a creature in an adjacent square. A reach weapon is a melee weapon that allows its wielder to strike at targets that aren’t adjacent to him or her. Glaives, guisarmes, lances, longspears, ranseurs, spiked chains, and whips are reach weapons. Ranged weapons are thrown weapons or projectile weapons that are not effective in melee. Melee weapons are used for making melee attacks, though some of them can be thrown as well. A character who uses a weapon with which he or she is not proficient takes a -4 penalty on attack rolls. Characters of other classes are proficient with an assortment of mainly simple weapons and possibly also some martial or even exotic weapons. Barbarians, fighters, paladins, and rangers are proficient with all simple and all martial weapons. These categories pertain to what training is needed to become proficient in a weapon’s use (simple, martial, or exotic), the weapon’s usefulness either in close combat (melee) or at a distance (ranged, which includes both thrown and projectile weapons), its relative encumbrance (light, one-handed, or two-handed), and its size (Small, Medium, or Large).Īnybody but a druid, monk, or wizard is proficient with all simple weapons. Weapons are grouped into several interlocking sets of categories. 7/24/2023 0 Comments Sniper elite v2 pricesDisguised as a German and working deep behind enemy lines you must stop Stalin's forces from gaining control of Germany's nuclear secrets. compares the cheapest prices of Sniper Elite V2 on the digital downloads market to find the best sales and discount codes on trusted stores. But its lower muzzle velocity leads to more bullet drop over longer ranges, challenging the. Caught in the life and death struggle between Soviets and Germans in war-torn Berlin, you control the fate of a lone American OSS Sniper. The Sniper Elite V2 DLC also includes two extra authentic sniping weapons the Soviet semi-automatic battle rifle SVT-40 and the standard German service rifle Kar 98: With its big clip and semi-automatic fire, SVT-40 is the brute of the sniping world. Find many great new & used options and get the best deals for Sniper Elite V2 Remastered NSW (nintendo Switch) - Game H4ln The Cheap Fast at the best online. Death, Evil Genius, Sniper Elite, Aliens versus Predator Classic 2000, Sniper Elite: Nazi Zombie Army, Ground Control Anthology, Ground Control II, Lords of the Realm III, Moonbase Commander, Lords of the Realm, Woolfe - The Red Hood Diaries, Battlezone 98 Redux, Sniper Elite 3 - Target Hitler: Hunt the Grey Wolf, Sniper Elite 3 - Camouflage Weapons Pack, Sniper Elite 3 - Hunter Weapons Pack, Sniper Elite 3 - Patriot Weapons Pack, Sniper Elite 3 - Sniper Rifle Weapons Pack, Sniper Elite 3 - Axis Weapons Pack, Sniper Elite 3 - Eastern Front Weapons Pack, Sniper Elite 3 - Allied Reinforcements Outfit Pack, Sniper Elite 3 - Save Churchill Part 1: In Shadows, Sniper Elite 3 - Save Churchill Part 2: Belly of the Beast, Sniper Elite 3 - Save Churchill Part 3: Confrontation, Sniper Elite 3 - International Camouflage Rifles Pack, Lords of the Realm II, Lords of Magic: Special Edition, Battlezone 98 Redux - The Red Odyssey, Sniper Elite 4 - Camouflage Rifles Skin Pack, Sniper Elite 4 - Silent Warfare Weapons Pack, Sniper Elite 4 - Covert Heroes Character Pack, Sniper Elite 4 - Target: Führer, Sniper Elite 4 - Deathstorm Part 1: Inception, Sniper Elite 4 - Deathstorm Part 2: Infiltration, Sniper Elite 4 - Deathstorm Part 3: Obliteration, Sniper Elite 4 - Lock and Load Weapons Pack, Sniper Elite 4 - Urban Assault Expansion Pack, Sniper Elite 4 - Night Fighter Expansion Pack, Sniper Elite 4 - Cold Warfare Winter Expansion Pack, Sniper Elite 4 - Allied Forces Rifle Pack, Sniper Elite 4Īs World War II draws to a close, the first covert battles of the Cold War begin. 4.02 Call of Duty Modern Warfare II - Beta Access Zombie Army 4 Dead War. Includes 41 items: Rogue Trooper, Judge Dredd: Dredd vs. Sniper Elite V2 Remastered - UPGRADE FOR ORIGINAL OWNERS Steam CD Key 2mo ago DRM: 8 risks with 0.61 fee 5.23 -15 with PEPPER15 Copy Sniper Elite Series (12) See All Sniper Elite 5 29.99 Sniper Elite VR 11.24 Sniper Elite V2 Remastered 3. Sniper Elite V2 Remastered Zombie Army Trilogy. 7/24/2023 0 Comments Google earth 3d models downloadOne benefit of a local coordinate system is that the exported scene is smaller in scale and makes it easier to handle in third-party software. The Local coordinate system is based on ENU coordinates, formed from a plane tangent to the Earth's surface fixed to the user defined Track Point. This is done by right clicking a Track Point in the Track Points panel, and select “Set as local origin”. When exporting Local Coordinates the world origin is specified by a user defined Track Point. As the origin point is consistent, this is useful when re-purposing graphics across multiple projects. Global coordinates are specified per ECEF (Earth Centered, Earth Fixed) which is a global coordinate system where the origin point is the center of the Earth, and the Z-axis extends North to South. Specifying world coordinates for exportĮarth Studio allows you to export your scene with a Global or Local coordinate system. Otherwise, composited elements will not line up with your Earth Studio footage. If there are, you'll need to re-render your project. jsx or JSON file.Įnsure that there are no differences between the camera in your tracking data and the camera motion from your rendered footage. Select which tracking elements you need (3D Camera and/or Track Points), and Earth Studio will begin downloading your tracking data as a. to export tracking data without re-rendering. For example, you might need to add additional track points to an existing animation.Īt any time, you can use File > Export > 3D Tracking Data. Some situations might require you to export tracking data for a project that has already been rendered. The tracking data script will be included with your image sequence and project file in the resulting zip. To get tracking data when you render, select the desired format under 3D Tracking Data in the Advanced Settings. This ensures that your camera and track points are perfectly up-to-date with the underlying footage. In most cases, it's best to export tracking data along with a render. jsx), which recreates the camera and any track points within a new After Effects composition. If you want to use your camera and track points outside of Earth Studio, you'll need to export that data in a format that a third-party program can understand.įor After Effects, this is an Adobe ExtendScript file (. Exporting Tracking Data from Earth Studio You can access the Track Point panel at any time from View > Track Points. Use the trash icon to delete a Track Point. From the panel, you can edit a Track Point's name, display color, or exact coordinates. Track Point PanelĪll existing Track Points are listed in the Track Point panel, which appears in the viewport whenever a new Track Point is created. Double-click to open the Track Point panel. Rename it by clicking on its name, and drag to change its location. The latitude and longitude will be defined by where you click, and the altitude will be defined by the ground level at that location.Ĭlick on a Track Point to select it. Track Points can also be created from the Top view. To move the Track Point to another location in the Camera view you can hold ⌥ while dragging the point. A new Track Point will be added at the location of your click. To set a Track Point, right-click anywhere in the Camera view and select Set Track Point from the menu. Take a look at our Permissions for more information about annotations and adding custom graphics over Google Earth imagery. Set a Track Point anywhere you plan to place an element in post-production, or set a few to use as reference. Track Points are represented as null objects in After Effects, and are helpful for positioning elements in your scene. You can also create and export Track Points along with a project's camera data. By natively exporting camera data from Earth Studio, you can be sure that composited elements will perfectly line up with your footage. text, borders, and shapes), more complicated elements must be added outside of Earth Studio.ģD Camera Export, currently compatible with Adobe ® After Effects ®, makes this process incredibly straightforward. While Overlays and KMLs enable the addition of simple elements to Earth imagery (e.g. With the ability to export camera data and tracking markers to post-production software, it's possible to seamlessly composite 2D and 3D elements into Earth Studio imagery. Animating in Earth Studio is incredibly powerful, but it's only the beginning. 7/24/2023 0 Comments Fast people searchThe FCRA forbids people search engines to get information about some persons because these search services are not consumer reporting agencies. There are, however, some restrictions in looking for people. You can use the website to look for anyone in the United States including friends and family members, partners, roommates, schoolmates, unknown callers, travel companions, sex offenders, and even yourself. It is essential to follow the rules laid down by the Fair Credit Reporting Act as regards people searches. Who am I Allowed to Look Up Using Fast People Finder? Click on search and go through the result page.Make sure it is the correct email address. Enter the email address of the individual you seek.With an email search, you’ll get the contact information of the owner as well as their social media accounts, shared multimedia, and Internet footprints. Hit enter and peruse the results that follow.This comprises the area code, the central office code, and the subscriber’s phone number. The number must correspond to the North American Numbering system. Write out the phone number of the person you want to find.From the options available, click on Phone Number Lookup.Click on the best match to get more information.Ī phone number lookup will return information such as social media profiles, addresses, and the name of the owner. Hit search and browse through the results that are returned.If it isn’t or you’re not sure, ignore the field. Include the location of the person if it is known.If there is a known middle name, also include it to help narrow the scope of your search. Input the first and last names of the person you’re looking for.Select the Name Search option from the list of available methods.The results to expect with this method include social media information, contact address, and pictures of the individual you seek. It is quite simple to find a person by name with Fast People Finder. You can either search for a person by name, phone number, or email address. There are several methods available for finding a person, allowing you to use any information you have to conduct your search. The user interface of Fast People Finder is incredibly straightforward to use. How to Find a Person Via Fast People Finder? You must therefore exercise patience in those kinds of situations to locate what you’re seeking ultimately. It could take several search attempts and going through more than the first page to get the exact information you need. This helps to narrow the scope of your search and get just the relevant results. Also, other details such as state, city, and zip code of residence should be included where they are known. The search box is filled up using the subject’s first and last names, as well as any known middle names. For this reason, conducting a proper people search requires a thorough examination of multiple official records. Even though your query brings results, there is no way to confirm that they are accurate. It’s a 100% free people finder and is quite easy to navigate.īecause a lot of people share the same name, it may be very difficult to find certain information about them such as their phone numbers and addresses. You only need to know how to use a simple website. With Fast People Finder, however, it’s way simpler. A people search website is usually required. This information is collected from several reliable authorized outlets, making sure it is accurate and credible.Ĭarrying out a people search more often than not comes with a cost. The search tool gives you a door to a variety of contact information, government records, and other background data. What is Fast People Finder?įast People Finder is a top-notch search engine that helps users to look up people using information like their names, mobile number, or email address. Do you know that there are websites that can help ease this? You just have to input certain details and you’re one step closer to finding that person. What do you do when you need to find people? It may be a friend you’ve not seen in a very long time, someone you recently met online, or the new neighbor downstairs. It makes life easy for us and is a vital step towards achieving success in any endeavor. This is why the importance of research cannot be overemphasized. You can’t solve all your problems yourself, be it at work or in your personal life. While there are people that are very intelligent and well-connected, everyone needs research. It is what separates what you know from what you do not know. It helps you get to new information quickly and also increases your level of knowledge. Research is important in all areas of life. 7/24/2023 0 Comments Retraction artifact meaningRetraction artifacts can be mistaken for LVI without IHC. Blood vessels more commonly invaded than lymph vessels. Results: LVI was associated with younger age ( P = 0.001), greater tumor size ( P = 0.007), higher Nottingham grade ( P = 0.001), higher LNR ( P = 0.001), higher NPI ( P = 0.001), Negative ER Status ( P = 0.001), Negative PR Status ( P = 0.002), Positive HER2/ neu status ( P = 0.021), Higher Intratumoral BMVD ( P = 0.016), Peritumoral BMVD ( P = 0.001), and Intratumoral LMVD ( P = 0.009). Statistical Analysis Used: SPSS Software Package. CD34 and D2-40 utilized to distinguish blood vessel, lymph vessel, and retraction artifacts and to calculate lymphatic microvessel density (LMVD) and blood microvessel density (BMVD). Correlation of LVI done with prognostic markers of Carcinoma Breast, namely, age of the patient, tumor size, Nottingham grade, lymph node ratio (LNR), Nottingham prognostic index (NPI), ER/PR status, and HER2/ neu status. Evaluation of formalin-fixed paraffin-embedded sections was done using H and E and IHC for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 HER2/ neu receptors, CD34, and D2-40 endothelial markers. Materials and Methods: Fifty mastectomy specimens diagnosed as infiltrating ductal carcinoma breast on histopathology selected for the study. Settings and Design: This was a prospective study. Aims: This study aims to confirm and analyze lymphovascular invasion (LVI) detected by hematoxylin and eosin (H and E) using IHC with CD34 and D2-40 and its correlation with other biologic and morphologic prognostic markers. Numerous prognostic factors based on morphology and immunohistochemistry (IHC) have been established which need to be interconnected to give patients best possible treatment. Sonal Agarwal, Amarjit Singh, Permeet Kaur Baggaĭepartment of Pathology, Government Medical College, Amritsar, Punjab, IndiaĬlick here for correspondence address and email Date of Web Publicationīackground: Carcinoma breast is ever-evolving and becoming increasingly prevalent in India. Immunohistochemical evaluation of lymphovascular invasion in carcinoma breast with CD34 and D2-40 and its correlation with other prognostic markers |